How Zomorph works
About 85% of the response seen with morphine administration is caused by zomorph-6-glucuronide. The mu and kappa opioid receptors are agonistically acted upon by zomorph and its metabolites. The effects of morphine on the brain’s ventral tegmental region depend critically on the mu-opioid receptor. While agonism of the mu-opioid receptor mediates respiratory system change and addiction problem, agonism of the delta-opioid receptor in the nucleus accumbens mediates Zomorph’s stimulation of the reward pathway Zomorph for sale .
Dosage
Oral-Moderate to severe pain:5-20 mg 4 hrly. Extended-release: 5-20 mg 12 hrly. Dosage is dependent on the severity of pain.
Intraspinal-Moderate to severe pain:Initially, 5 mg epidural inj; after 1 hr, additional doses of 1-2 mg may be given up to a total dose of 10 mg/24 hr if pain relief is unsatisfactory. A dose of 20-30 mg daily may be required in some patients. Liposomal inj: 10-20 mg depending on the type of surgery.
Intrathecal-Moderate to severe pain: 0.2-1 mg once daily or 1-10 mg daily for patients with opioid tolerance. Some patients may require a dose of up to 20 mg daily.
Intravenous-Acute pulmonary oedema Zomorph for sale:
- Adult: 5-10 mg via slow inj at 2 mg/min.
- Elderly: Half of the usual adult dose.
Intravenous-
Pain associated with myocardial infarction:
- Adult: 5-10 mg at 1-2 mg/min followed by a further 5-10 mg as necessary.
- Elderly: Half of the usual adult dose Zomorph 100mg .
Parenteral-
- Moderate to severe pain:5-20 mg; 2.5-10 mg via slow IV inj over 4-5 min with patient in recumbent position or a starting dose of 1-2 mg/hr via continuous IV infusion (max: 100 mg/day; 4 g/day in cancer patients). Doses may be adjusted according to severity of pain and patient’s response Zomorph 100mg .
- Premedication in surgery:Up to 10 mg, given 60-90 min before operation Buy Zomorph.
May be taken with or without food. May be taken with meals to reduce GI discomfort Buy Zomorph .
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